We do not yet know whether a damaged barrier is truly responsible for Alzheimer’s or other brain illnesses. It could play a contributing role along with other causes, including genetics and a variety of cellular problems that have been observed in aging brains. Lots of brain cells get hurt, and key neural circuits are modified or weakened, so their functions deteriorate. Credit: Now Medical StudiosThe sequence shows up in the aging brain as well, as we learned by looking for it in mice. But our intervention research may indicate that in the absence of a lot of cell death, the aging brain has a hidden capacity to rebound from some types of insults.