For patients with Alzheimer’s, Huntington’s and many other dementia-causing diseases, however, memory loss is much more profound. Given the steady rise in the numbers of Alzheimer’s patients, in particular, the research community and pharmaceutical companies agree that the development of treatment strategies is critical, now more than ever. This would be like asking Alzheimer’s patients to remember something that hasn’t been stored in their brain in the first place. This was the very first time that I started to believe in the “weakened memory recall” idea for Alzheimer’s disease. Together, these studies suggested that “weakened memory recall” might not only be applicable to early Alzheimer’s but potentially to other human diseases that also affect our memories.