In this issue of Scientific American, we show what scientists have learned so far about the structure and function of the evil genius pathogen SARS-CoV-2. Researchers are studying the effects of mass isolation, fear and grief and the ways discrimination and poverty make this pandemic even more devastating. The consensus here at Scientific American is that neutrinos are cool. I'm thrilled to join Scientific American as the next editor in chief in our 175-year history. Thank you for supporting the magazine and being part of the Scientific American community.