No doubt you’ve heard about the novel coronavirus variants that are evolving around the world. One pattern we see is called convergent evolution, where the same trait emerges in different independent lineages over time, usually as they adapt to similar environments. With the benefit of increased genome surveillance of the coronavirus, several recent studies have identified signatures of convergent evolution. These viral adaptations are already rewriting our biology textbooks on convergent evolution; let’s strive to limit new material. It’s also critical that we make significant investments in building an early-warning system to detect new SARS-CoV-2 variants as well as many other emerging pathogens, both known and yet to be discovered.